Search results for "Multicentric study"

showing 5 items of 5 documents

Cognitive functioning throughout adulthood and illness stages in individuals with psychotic disorders and their unaffected siblings

2021

The European Community’s Seventh Framework Programme under grant agreement No. HEALTH-F2-2010-241909 (EUGEI); The Spanish sample was supported by the Spanish Ministry of Science and Innovation, Instituto de Salud Carlos III (SAM16PE07CP1, PI16/02012, PI19/024) (...)

0301 basic medicinevaliditymedicine.medical_treatmentCHILDHOODNeuropsychological TestsFAMÍLIAepisodeCognition0302 clinical medicineDEFICITSSettore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat.MedicineCognitive impairmentPsychiatrySymptom severityCannabis useIMPAIRMENTABILITYPsychiatry and Mental healthSchizophreniaRELIABILITYNeuropsychological TestLife Sciences & BiomedicineHumanClinical psychologyAdultBiochemistry & Molecular Biologyimpairmentschizophrenia-patientsabilityGENETIC RISKPsychotic DisorderSCHIZOPHRENIA-PATIENTS03 medical and health sciencesCellular and Molecular NeuroscienceSDG 3 - Good Health and Well-beingSettore M-PSI/08 - Psicologia ClinicaHumansIn patientCognitive skillVALIDITYAntipsychoticMolecular BiologySettore MED/25 - PsichiatriaAgedCross-Sectional StudieDECLINEScience & Technologyreliabilitybusiness.industryWorking memorySiblingsNeurosciencesDiagnostic markersmedicine.diseaseCross-Sectional Studies030104 developmental biologydeficitsPsychotic DisordersSchizophreniaPSYCHOSIS COGNITION MULTICENTRIC STUDYNeurosciences & NeurologybusinessEPISODE030217 neurology & neurosurgeryMolecular Psychiatry
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IQ differences between patients with first episode psychosis in London and Palermo reflect differences in patterns of cannabis use.

2019

Aims: Cognitive impairment is a possible indicator of neurodevelopmental impairment, but not all psychotic patients are cognitively compromised. It has been suggested that heavy cannabis use may precipitate psychosis in those who show no such compromise. This study compares two samples of patients with first-episode psychosis and their respective non-psychotic controls, in London (UK) and Palermo (Italy), and examines whether different patterns of cannabis use are reflected in differences in IQ. Methods: The two studies used the same inclusion/exclusion criteria and instruments. The sample comprised 249 subjects from London (106 patients and 143 controls) and 247 subjects from Palermo (120 …

AdultCross-Cultural ComparisonMalePsychosismedicine.medical_specialtyAdolescentIntelligenceNeurodevelopmentYoung Adult03 medical and health sciences0302 clinical medicineCognitionFirst episode psychosisLondonmedicineSettore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat.HumansCognitive DysfunctionIn patientCannabiPsychiatryCognitive impairmentSettore MED/25 - PsichiatriaBiological PsychiatryMulticentric studybiologybusiness.industryConfoundingCognitionCannabis usemedicine.diseasebiology.organism_classification030227 psychiatryPsychiatry and Mental healthItalyPsychotic DisordersRisk factorsCase-Control StudiesFemaleMarijuana UseCannabisbusiness030217 neurology & neurosurgery
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Acute and chronic hepatitis in childhood leukemia: a multicentric study from the Italian Pediatric Cooperative Group for Therapy of Acute Leukemia (A…

1985

The incidence of acute and chronic liver damage and its relation to hepatitis B virus (HBV) infection was evaluated in 164 consecutive children with acute leukemia seen in ten Italian hemato-pediatric units. Thirteen out of 164 children (7.9%) had acute hepatitis (AH) during treatment, while 8/90 (8.8%) showed an acute exacerbation of liver damage within 6 months after therapy withdrawal. Seven of the 13 children with AH while on therapy were HBsAg positive. In 12/13 cases, liver disease progressed to chronicity. Five of eight children who developed AH after completion of treatment were HBsAg positive. Eighty-nine patients (54.2%) developed biochemical evidence of chronic hepatitis during t…

MaleCancer Researchmedicine.medical_specialtyHBsAgChildhood leukemiaExacerbationAdolescentmedicine.disease_causeGastroenterologyacute hepatitisHepatitisLiver diseasechronic hepatitiLiver Function TestsInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansChildHepatitis B virusAcute leukemiaHepatitis B Surface AntigensLeukemiabusiness.industryLiver cellacute hepatitichildhood leukemiavirus diseasesInfantmedicine.diseaseacute hepatitis; chronic hepatitis; childhood leukemiaHepatitis BLeukemia LymphoidLeukemiaAcute and chronic hepatitis; childhood leukemia; multicentric study from AIEOPOncologyItalyChild PreschoolPediatrics Perinatology and Child HealthImmunologyAcute DiseaseFemalechronic hepatitisChemical and Drug Induced Liver InjurybusinessMedical and pediatric oncology
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Nonalcoholic fatty liver and metabolic syndrome in Italy: Results from a multicentric study of the Italian Arteriosclerosis society

2013

Nonalcoholic fatty liver disease (NAFLD) is associated with all the components of metabolic syndrome (MS) and might to be considered an additional component of MS itself. The Italian Society for the Study of Atherosclerosis (SISA) in 2005 started a research project aimed to study the NAFLD, using ultrasound (US), in nondiabetic MS subjects matching at least one of the ATP III criteria for HDL-C or triglycerides [TG]. Prevalence of US-NAFLD and its associated risk factors and prevalence of hypertransaminasemia and its possible determinants were evaluated. NAFLD prevalence was 0.78. Men with steatosis compared to men without steatosis were younger (P < 0.05) with higher TG (P < 0.03), homeost…

MaleSettore MED/09 - Medicina InternaEndocrinology Diabetes and MetabolismNonalcoholic fatty liverSex FactorSettore MED/13 - EndocrinologiaBody Mass IndexEndocrinologyNon-alcoholic Fatty Liver DiseaseRisk FactorsNonalcoholic fatty liver diseaseAtherosclerosis; Metabolic Syndrome X; Sex Factors; Humans; Lipids; Aged; Fatty Liver; Non-alcoholic Fatty Liver Disease; Body Mass Index; Italy; Logistic Models; Risk Factors; Liver; Middle Aged; Female; MaleUltrasonographyMulticentric studyMetabolic Syndrome XFatty liverGeneral MedicineArteriosclerosisLipidMiddle AgedLipidsMetabolic syndromeDiabetes and MetabolismItalyLiverAtherosclerosiFemaleHumanmedicine.medical_specialtyLogistic ModelNonalcoholic fatty liver Metabolic syndrome Lipids Multicentric studyInsulin resistanceSex FactorsDiabetes mellitusInternal medicinemedicineInternal MedicineHumansLipids; Metabolic syndrome; Multicentric study; Nonalcoholic fatty liver; Aged; Body Mass Index; Fatty Liver; Female; Humans; Italy; Lipids; Liver; Logistic Models; Male; Metabolic Syndrome X; Middle Aged; Non-alcoholic Fatty Liver Disease; Risk Factors; Sex Factors; Atherosclerosis; Endocrinology; Internal Medicine; Endocrinology Diabetes and MetabolismAgedbusiness.industryRisk Factornutritional and metabolic diseasesAmbientalemedicine.diseaseAtherosclerosisFatty LiverEndocrinologyLogistic ModelsMetabolic syndromeSteatosisbusinessBody mass index
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Reverse transcriptase loop-mediated isothermal amplification (RT-LAMP) as a user-friendly system to detect SARS-CoV-2 infection: a multicentric study

2021

Although reverse transcriptase quantitative PCR remains the gold standard to perform viral detection, reverse transcriptase loop-mediated isothermal amplification (RT-LAMP) is already used to perform diagnosis of various infections. This work reports the results of a multicentric study performed in Sicily to evaluate the diagnostic power of an RT-LAMP kit for the diagnosis of SARS-CoV-2 infection on a total of 551 samples collected in January and February 2021, revealing sensitivity, specificity, accuracy, positive and negative predictive values ≥95%. Our results suggest the potential employment of this kit as a screening test to be used where fast and reliable results are demanded without …

Multicentric studyRT-LAMP.Diagnostic powerReverse Transcriptase Polymerase Chain ReactionSARS-CoV-2COVID-19RNA-Directed DNA PolymeraseSensitivity and SpecificityMolecular Diagnostic TechniquesHumansRNA ViralRNAViralNucleic Acid Amplification Techniques
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